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1

DARK Classics in Chemical Neuroscience: Methamphetamine

Abbruscato, Thomas J, Trippier, Paul C.

Journal:

ACS Chemical Neuroscience

Year:

2018

Language:

english

File:

PDF, 304 KB

english, 2018

2

Developments in environmental policy at the european level - a government view

Journal:

Environmental Policy and Governance

Year:

1991

Language:

english

File:

PDF, 505 KB

english, 1991

3

Current and Emerging Pharmacological Targets for the Treatment of Alzheimer’s Disease

Morsy, Ahmed, Trippier, Paul C.

Journal:

Journal of Alzheimer's Disease

Year:

2019

Language:

english

File:

PDF, 1.93 MB

english, 2019

4

Anwendung der statistischen Versuchsplanung und -auswertung bei der Entwicklung einer Emailliertechnologie/ Application of statistical experiment planning and evaluation during the development of an enamelling technology

Schäfer, Wolfgang, Trippier, Gisela, Hahn, Aribert

Journal:

at - Automatisierungstechnik

Year:

1992

Language:

german

File:

PDF, 1.53 MB

german, 1992

5

The health of prisoners: summary of NICE guidance

Bradshaw, Richard, Pordes, Ben A J, Trippier, Hannah, Kosky, Nick, Pilling, Steve, O’Brien, Fionnuala

Journal:

Year:

2017

Language:

english

File:

PDF, 1.05 MB

english, 2017

6

Small molecule inhibitors for acute myeloid leukemia: where is the field heading?

Trippier, Paul C

Journal:

Future Medicinal Chemistry

Year:

2017

Language:

english

File:

PDF, 1.16 MB

english, 2017

7

Lacunar Infarcts, but Not Perivascular Spaces, Are Predictors of Cognitive Decline in Cerebral Small-Vessel Disease

Benjamin, Philip, Trippier, Sarah, Lawrence, Andrew J., Lambert, Christian, Zeestraten, Eva, Williams, Owen A., Patel, Bhavini, Morris, Robin G., Barrick, Thomas R., MacKinnon, Andrew D., Markus, Hugh

Journal:

Year:

2018

Language:

english

File:

PDF, 1.85 MB

english, 2018

8

Amyloid-Binding Alcohol Dehydrogenase (ABAD) Inhibitors for the Treatment of Alzheimer’s Disease

Morsy, Ahmed, Trippier, Paul C.

Journal:

Journal of Medicinal Chemistry

Year:

2018

Language:

english

File:

PDF, 741 KB

english, 2018

9

Tourism in the 1990s — UK government view

Journal:

Tourism Management

Year:

1987

Language:

english

File:

PDF, 391 KB

english, 1987

10

Waste management and the development of standards

David A. Trippier

Journal:

Year:

1990

Language:

english

File:

PDF, 470 KB

english, 1990

11

(1) Science and policy

Journal:

Year:

1992

Language:

english

File:

PDF, 76 KB

english, 1992

12

Biomimetic synthesis, antibacterial activity and structure–activity properties of the pyroglutamate core of oxazolomycin

Angelov, Plamen, Chau, Yui Kwan Sonia, Fryer, Paul J., Moloney, Mark G., Thompson, Amber L., Trippier, Paul C.

Journal:

Organic & Biomolecular Chemistry

Year:

2012

Language:

english

File:

PDF, 1.02 MB

english, 2012

13

Synthetic Strategies for the Biotinylation of Bioactive Small Molecules

Trippier, Paul C.

Journal:

Year:

2013

Language:

english

File:

PDF, 892 KB

english, 2013

14

Target- and Mechanism-Based Therapeutics for Neurodegenerative Diseases: Strength in Numbers

Trippier, Paul C., Jansen Labby, Kristin, Hawker, Dustin D., Mataka, Jan J., Silverman, Richard B.

Journal:

Journal of Medicinal Chemistry

Year:

2013

Language:

english

File:

PDF, 1.64 MB

english, 2013

15

Substituted pyrazolones require N2 hydrogen bond donating ability to protect against cytotoxicity from protein aggregation of mutant superoxide dismutase 1

Trippier, Paul C., Benmohamed, Radhia, Kirsch, Donald R., Silverman, Richard B.

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2012

Language:

english

File:

PDF, 643 KB

english, 2012

16

Remarkable Stereospecific Conjugate Additions to the Hsp90 Inhibitor Celastrol

Klaić, Lada, Trippier, Paul C., Mishra, Rama K., Morimoto, Richard I., Silverman, Richard B.

Journal:

Journal of the American Chemical Society

Year:

2011

Language:

english

File:

PDF, 1.11 MB

english, 2011

17

Corrigendum to “Substituted pyrazolones require N2 hydrogen bond donating ability to protect against cytotoxicity from protein aggregation of mutant superoxide dismutase 1” [Bioorg. Med. Chem. Lett. 22 (2012) 6647–6650]

Trippier, Paul C., Benmohamed, Radhia, Kirsch, Donald R., Silverman, Richard B.

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2014

Language:

english

File:

PDF, 180 KB

english, 2014

18

Exploration of relative chemoselectivity in the hydrodechlorination of 2-chloropyridines

Kinarivala, Nihar, Trippier, Paul C.

Journal:

Tetrahedron Letters

Year:

2014

Language:

english

File:

PDF, 2.03 MB

english, 2014

19

Boronic acids in medicinal chemistry: anticancer, antibacterial and antiviral applications

Trippier, Paul C., McGuigan, Christopher

Journal:

Year:

2010

Language:

english

File:

PDF, 261 KB

english, 2010

20

Proteasome Activation is a Mechanism for Pyrazolone Small Molecules Displaying Therapeutic Potential in Amyotrophic Lateral Sclerosis

Trippier, Paul C., Zhao, Kevin Tianmeng, Fox, Susan G., Schiefer, Isaac T., Benmohamed, Radhia, Moran, Jason, Kirsch, Donald R., Morimoto, Richard I., Silverman, Richard B.

Journal:

ACS Chemical Neuroscience

Year:

2014

Language:

english

File:

PDF, 1.66 MB

english, 2014

21

A multicomponent coupling strategy suitable for the synthesis of the triene component of the oxazolomycin antibioticsThis is one of a number of contributions from the current members of the Dyson Perrins Laboratory to mark the end of almost 90 years of organic chemistry research in that building, as all its current academic staff move across South Parks Road to a new purpose-built laboratory.

Bulger, Paul G., Moloney, Mark G., Trippier, Paul C.

Journal:

Organic & Biomolecular Chemistry

Year:

2003

Language:

english

File:

PDF, 280 KB

english, 2003

22

Screening baccharin analogs as selective inhibitors against type 5 17β-hydroxysteroid dehydrogenase (AKR1C3)

Zang, Tianzhu, Verma, Kshitij, Chen, Mo, Jin, Yi, Trippier, Paul C., Penning, Trevor M.

Journal:

Chemico-Biological Interactions

Year:

2015

Language:

english

File:

PDF, 2.36 MB

english, 2015

23

Right hemisphere control of visuospatial attention in near space

Longo, Matthew R., Trippier, Sarah, Vagnoni, Eleonora, Lourenco, Stella F.

Journal:

Neuropsychologia

Year:

2015

Language:

english

File:

PDF, 2.43 MB

english, 2015

24

Phenylboronic-acid-based carbohydrate binders as antiviral therapeutics: bisphenylboronic acids

Trippier, Paul C, Balzarini, Jan, McGuigan, Christopher

Journal:

Antiviral Chemistry & Chemotherapy

Year:

2010

Language:

english

File:

PDF, 585 KB

english, 2010

25

A Multicomponent Coupling Strategy for the Synthesis of the Triene Component of the Oxazolomycin Antibiotics

Bulger, Paul G., Moloney, Mark G., Trippier, Paul C.

Journal:

Year:

2002

Language:

english

File:

PDF, 45 KB

english, 2002

26

Progress in the Development of Small Molecule Therapeutics for the Treatment of Neuronal Ceroid Lipofuscinoses (NCLs)

Kinarivala, Nihar, Trippier, Paul C.

Journal:

Journal of Medicinal Chemistry

Year:

2015

Language:

english

File:

PDF, 2.26 MB

english, 2015

27

Pharmacophore elucidation of phosphoiodyn A – Potent and selective peroxisome proliferator-activated receptor β/δ agonists with neuroprotective activity

Kinarivala, Nihar, Suh, Ji Ho, Botros, Mina, Webb, Paul, Trippier, Paul C.

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2016

File:

PDF, 783 KB

2016

28

Pharmacophore elucidation of phosphoiodyn A – Potent and selective peroxisome proliferator-activated receptor β/δ agonists with neuroprotective activity

Kinarivala, Nihar, Suh, Ji Ho, Botros, Mina, Webb, Paul, Trippier, Paul C.

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2016

Language:

english

File:

PDF, 783 KB

english, 2016

29

Reflections on the role of the specialist dual diagnosis clinician

Trippier, Justine, Parker, Stephen

Journal:

Advances in Dual Diagnosis

Year:

2008

Language:

english

File:

PDF, 73 KB

english, 2008

30

Selective AKR1C3 inhibitors potentiate chemotherapeutic activity in multiple acute myeloid leukemia (AML) cell lines

Verma, Kshitij, Zang, Tianzhu, Gupta, Nehal, Penning, Trevor M., Trippier, Paul C.

Journal:

ACS Medicinal Chemistry Letters

Year:

2016

Language:

english

File:

PDF, 822 KB

english, 2016

31

1. The Role of Government in Fostering Industrial and Environmental Links

Journal:

Year:

1988

Language:

english

File:

PDF, 711 KB

english, 1988

32

ChemInform Abstract: Synthetic Strategies for the Biotinylation of Bioactive Small Molecules

Trippier, Paul C.

Journal:

Year:

2013

File:

PDF, 18 KB

2013

33

PROGRESS update

Trippier, Justine

Journal:

Advances in Dual Diagnosis

Year:

2010

Language:

english

File:

PDF, 105 KB

english, 2010

34

Passage Variation of PC12 Cells Results in Inconsistent Susceptibility to Externally Induced Apoptosis

Kinarivala, Nihar, Shah, Kaushik, Abbruscato, Thomas J, Trippier, Paul C.

Journal:

ACS Chemical Neuroscience

Year:

2016

Language:

english

File:

PDF, 1.20 MB

english, 2016

35

Synthesis and Antineoplastic Evaluation of Mitochondrial Complex II (Succinate Dehydrogenase) Inhibitors Derived from Atpenin A5

Wang, Hezhen, Huwaimel, Bader, Verma, Kshitij, Miller, James, Germain, Todd, Kinarivala, Nihar, Pappas, Dimitri, Brookes, Paul, Trippier, Paul Charles

Journal:

Year:

2017

Language:

english

File:

PDF, 1.91 MB

english, 2017

36

Phenylboronic-acid-based carbohydrate binders as antiviral therapeutics: monophenylboronic acids

Trippier, Paul C, McGuigan, Christopher, Balzarini, Jan

Journal:

Antiviral Chemistry & Chemotherapy

Year:

2010

Language:

english

File:

PDF, 267 KB

english, 2010

37

Discovery of Aromatic Carbamates that Confer Neuroprotective Activity by Enhancing Autophagy and Inducing the Anti-Apoptotic Protein B-cell lymphoma 2 (Bcl-2)

Kinarivala, Nihar, Patel, Ronak, Boustany, Rose-Mary, Al-Ahmad, Abraham J., Trippier, Paul C.

Journal:

Journal of Medicinal Chemistry

Year:

2017

Language:

english

File:

PDF, 2.96 MB

english, 2017

38

Molecule of the Month: Relating Organic Chemistry Principles to Drug Action

Trippier, Paul C.

Journal:

Journal of Chemical Education

Year:

2018

Language:

english

File:

PDF, 413 KB

english, 2018

39

AKR1C3 Inhibitor KV-37 Exhibits Antineoplastic Effects and Potentiates Enzalutamide in Combination Therapy in Prostate Adenocarcinoma Cells

Verma, Kshitij, Gupta, Nehal, Zang, Tianzhu, Wangtrakuldee, Phumvadee, Srivastava, Sanjay K, Penning, Trevor M., Trippier, Paul C

Journal:

Molecular Cancer Therapeutics

Year:

2018

Language:

english

File:

PDF, 8.40 MB

english, 2018

40

Flupirtine derivatives as potential treatment for the neuronal ceroid lipofuscinoses

Makoukji, Joelle, Saadeh, Fadi, Mansour, Karl Albert, El-Sitt, Sally, Al Ali, Jamal, Kinarivala, Nihar, Trippier, Paul C., Boustany, Rose-Mary

Journal:

Annals of Clinical and Translational Neurology

Year:

2018

Language:

english

File:

PDF, 711 KB

english, 2018

41

Selecting Good ‘Drug-Like’ Properties to Optimize Small Molecule Blood-Brain Barrier Penetration

C. Trippier, Paul

Journal:

Current Medicinal Chemistry

Year:

2016

File:

PDF, 1.17 MB

2016

42

Potent and Highly Selective Aldo–Keto Reductase 1C3 (AKR1C3) Inhibitors Act as Chemotherapeutic Potentiators in Acute Myeloid Leukemia and T-Cell Acute Lymphoblastic Leukemia

Verma, Kshitij, Zang, Tianzhu, Penning, Trevor M., Trippier, Paul C.

Journal:

Journal of Medicinal Chemistry

Year:

2019

File:

PDF, 2.19 MB

2019

43

P117 Predictive factors of outcome in poor grade subarachnoid haemorrhage (SAH)

Fahmy, J, Boumrah, T, Trippier, S, Hainsworth, A, Madigan, J, Pereira, E, Shtaya, A, Minhas, P

Journal:

Journal of Neurology Neurosurgery & Psychiatry

Year:

2019

Language:

english

File:

PDF, 48 KB

english, 2019

44

P112 Management and outcome of subarachnoid haemorrhage (SAH) in older people: a centre series

Boumrah, T, Fahmy, J, Trippier, S, Hainsworth, A, Madigan, J, Pereira, E, Minhas, P, Shtaya, A

Journal:

Journal of Neurology Neurosurgery & Psychiatry

Year:

2019

Language:

english

File:

PDF, 49 KB

english, 2019

45

Reversal of Apalutamide and Darolutamide Aldo-Keto Reductase 1C3-Mediated Resistance by a Small Molecule Inhibitor

Morsy, Ahmed, Trippier, Paul C.

Journal:

ACS Chemical Biology

Year:

2020

File:

PDF, 507 KB

2020

46

The current state of drug repurposing and rare diseases: an interview with Paul Trippier

Trippier, Paul C

Journal:

Future Drug Discovery

Year:

2020

File:

PDF, 342 KB

2020

47

Amide Bond Bioisosteres: Strategies, Synthesis and Successes

Kumari, Shikha, Carmona, Angelica, Tiwari, Amit K., Trippier, Paul C.

Journal:

Journal of Medicinal Chemistry

Year:

2020

File:

PDF, 4.77 MB

2020

48

Comment on âStroke in patients with SARSâCoVâ2 infection: case seriesâ from a London hospital experience

Shtaya, Anan, Trippier, Sarah, Ghatala, Rita, Cluckie, Gillian, Zhang, Liqun

Journal:

Journal of Neurology

Year:

2020

File:

PDF, 402 KB

2020

49

Exogenous Flupirtine as Potential Treatment for CLN3 Disease

Maalouf, Katia, Makoukji, Joelle, Saab, Sara, Makhoul, Nadine J., Carmona, Angelica V., Kinarivala, Nihar, Ghanem, NoÃ«l, Trippier, Paul C., Boustany, Rose-Mary

Journal:

Year:

2020

File:

PDF, 4.47 MB

2020

50

An iPSC-Derived Neuron Model of CLN3 Disease Facilitates Small Molecule Phenotypic Screening

Kinarivala, Nihar, Morsy, Ahmed, Patel, Ronak, Carmona, Angelica, Sajib, Md Sanaullah, Raut, Snehal, Mikelis, Constantinos, Al-Ahmad, Abraham J., Trippier, Paul C.

Journal:

ACS Pharmacology & Translational Science

Year:

2020

File:

PDF, 1.41 MB

2020